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This peptide sequence, biotin-GRPRTSSFAEG, corresponds to the sequence of GSK3 surrounding the serine phosphorylated by MAP kinase activated protein kinase (MAPKAP kinase-1) and p70 ribosomal S6 kinase. Acts as a substrate for Akt (PKB), Km=4 µM. The N-terminal biotin allows this peptide to be used in kinase assays with streptavidin-bound membranes.
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RUO – Research Use Only |
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