Highly sensitive corticosterone ELISA kit, species independent, used for animal stress research.
- Sensitive measurement of Corticosterone, detecting as little as 27 pg/ml
- High throughput format with results in 3 hours for up to 39 samples in duplicate
- Broad dynamic range
- Species independent
- Routinely used to monitor stress levels in zoo animals
The Corticosterone ELISA kit is a colorimetric competitive enzyme immunoassay kit with results in 3 hours. Absorbance is read at 405 nm. The Corticosterone ELISA kit has low cross-reactivity with related steroids. The broad dynamic range makes this kit ideal for a wide variety of sample matrices from any species.
Corticosterone is a glucocorticoid secreted by the cortex of the adrenal gland. Corticosterone is produced in response to the stimulation of the adrenal cortex by adrenocorticotropic hormone (ACTH) and is the precursor of aldosterone. Corticosterone production has been shown to increase with stress, with elevated corticosterone levels being associated with impairment of long term memory retrieval and following burn injury. In addition to stress levels, corticosterone is believed to play a decisive role in sleep-wake patterns.
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Product Details
Application |
Colorimetric detection, ELISA |
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Application Notes |
For the quantitative determination of Corticosterone in culture supernatants, feces, plasma, serum, and saliva from any species. Cited sample types include cell lysate, urine and whole blood. |
Assay Time |
3 hours |
Compatibility |
This product is compatible with the Absorbance 96 Plate Reader. |
Contents |
DxS IgG Microtiter plate, Assay buffer 15 concentrate, Steroid displacement reagent, Conjugate, Antibody, Wash buffer concentrate, Standard, pNpp Substrate, Stop solution |
Crossreactivity |
Corticosterone (100%), Deoxycorticosterone (21.3%), Desoxycorticosterone (21.0%), Progesterone (0.46%), Testosterone (0.31%), Tetrahydrocorticosterone (0.28%), Aldosterone (0.18%), Cortisol (0.046%) and <0.03%: Pregnenolone, Estradiol, Cortisone, 11-dehydrocorticosterone acetate |
Sensitivity |
27.0 pg/ml (range 32 – 20,000 pg/ml) |
Species Reactivity |
Species independent |
Technical Info / Product Notes |
Cited samples: |
Wavelength |
405 nm |
Handling & Storage
Long Term Storage |
+4°C |
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Shipping |
Blue Ice |
Regulatory Status |
RUO – Research Use Only |
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- Early-life stress induces persistent astrocyte dysfunction associated with fear generalisation: Guayasamin, M., Depaauw-Holt, L. R., et al.; Elife 13, RP99988 (2025), Abstract
- Edaravone Attenuates Sleep Deprivation-Induced Memory Deficits by Inhibiting Oxidative Stress and Neuroinflammation in Murine Models: Ji, S., Dong, Y., et al.; Biomedicines 13, 1047 (2025), Abstract
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- Genomic glucocorticoid receptor effects guide acute stress-induced delayed anxiety and basolateral amygdala spine plasticity in rats: L.S. Novaes, et al.; Neurobiol. Stress 28, 100589 (2024), Abstract
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- Functional Differentiation along the Rostro-Caudal Axis of the Avian Hippocampal Formation: K.S. Gonzalez, et al.; Brain Behav. Evol. , (2024), Abstract
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- Ablation of PC1/3 in POMC-Expressing Tissues but Not in Immune Cells Induces Sepsis Hypersensitivity: Moeller, J., Meier, D. T., et al.; J. Endocr. Soc. 8, bvae171 (2024), Abstract
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- Alterations in the Hypothalamic-Pituitary-Adrenal Axis as a Response to Experimental Autoimmune Encephalomyelitis in Dark Agouti Rats of Both Sexes: Milosevic, A., Milosevic, K., et al.; Biomolecules 14, (2024), Abstract
- Antidepressant Effect of Enzymatic Porcine Placenta Hydrolysate in Repeated Immobilization Stress-Induced Ovariectomized Female Mice: Ye, M., Nguyen, S., et al.; Curr. Issues Mol. Biol. 46, 6121 (2024), Abstract
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- Astrocytic inhibition of lateral septal neurons promotes diverse stress responses: Seo, K., Won, S., et al.; Nat. Commun. 15, 10091 (2024), Abstract
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- Co and N2 Are No Humane Alternatives to Co2 Euthanasia in Rats: Seebeck, P., Calvet, C., et al.; Research Square , (2024)
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- Comparative Impact of Alternate-Day Fasting and Time-Restricted Feeding on Placental Function and Fetal Development in Maternal Obesity: Liu, S., Hua, L., et al.; Nutrients 17, (2024), Abstract
- Daily fluctuations in blood glucose with normal aging are inversely related to hippocampal synaptic mitochondrial proteins: Braunstein, P. W., Horovitz, D. J., et al.; Aging Brain 5, 100116 (2024), Abstract
- Dietary inclusion of a Saccharomyces cerevisiae metabolite improved reproductive performance but did not affect intestinal permeability in two chicken meat breeder lines: Forder, R. E., Willson, N. L., et al.; Poult. Sci. 103, 103595 (2024), Abstract
- Differential regulation of innate immune system in frontal cortex and hippocampus in a double-hit neurodevelopmental model in rats: Bris, Á. G., Macdowell, K. S., et al.; Neurotherapeutics 21, e00300 (2024), Abstract
- Dorsal peduncular cortex activity modulates affective behavior and fear extinction in mice: Botterill, J. J., Khlaifia, A., et al.; Neuropsychopharmacology 49, 993 (2024), Abstract
- Dorsomedial Ventromedial Hypothalamic Nucleus Growth Hormone-Releasing Hormone Neuron Steroidogenic Factor-1 Gene Targets in Female Rat: Sapkota, S., Roy, S. C., et al.; ASN Neuro 16, 2403345 (2024), Abstract
- Early life conditions reduce similarity between reproductive partners in HPA axis response to stress: Kriengwatana, B. P., Marshall, C. J., et al.; Horm. Behav. 162, 105508 (2024), Abstract
- Effect of Dietary Crude Protein Reduction Levels on Performance, Nutrient Digestibility, Nitrogen Utilization, Blood Parameters, Meat Quality, and Welfare Index of Broilers in Welfare-Friendly Environments: Son, J., Lee, W. D., et al.; Animals (Basel) 14, (2024), Abstract
- Effect of Feeding Sugarcane Bagasse-Extracted Polyphenolic Mixture on the Growth Performance, Meat Quality, and Oxidative and Inflammatory Status of Chronic Heat-Stressed Broiler Chickens: Kikusato, M., Namai, F., et al.; Animals (Basel) 14, (2024), Abstract
- Effects of grain-based pecking blocks on productivity and welfare indicators in commercial broiler chickens: Kwon, B. Y., Lee, H. G., et al.; Anim. Biosci. 37, 536 (2024), Abstract
- Effects of Ketogenic Diet on Increased Ethanol Consumption Induced by Social Stress in Female Mice: Torres-Rubio, L., Reguilón, M. D., et al.; Preprints.org , (2024)
- Eurycoma longifolia (Tongkat Ali) supplementation enhances sleep and wake consolidation in wild-type, but not in narcoleptic mice: Sakai, N., Komi, K., et al.; Sleep Adv. 5, zpae047 (2024), Abstract
- Extremely Low-Frequency Electromagnetic Field (ELF-EMF) Increases Mitochondrial Electron Transport Chain Activities and Ameliorates Depressive Behaviors in Mice: Teranishi, M., Ito, M., et al.; Int. J. Mol. Sci. 25, (2024), Abstract
- Feedforward inhibition of stress by brainstem neuropeptide Y neurons: Zhang, Y., Shen, J., et al.; Nat. Commun. 15, 7603 (2024), Abstract
- Female zebra finches are more vulnerable to social isolation stress than males: Involvement of the nonapeptide system: Wang, L., Hao, Z., et al.; Zool. Res. 45, 1300 (2024), Abstract
- Glucose transporter-2 regulation of VMN GABA neuron metabolic sensor and transmitter gene expression: Roy, S. C., Sapkota, S., et al.; Sci. Rep. 14, 14220 (2024), Abstract
- Juvenile/Peripubertal Exposure to Omega-3 and Environmental Enrichment Differentially Affects CORT Secretion and Adulthood Stress Coping, Sociability, and CA3 Glucocorticoid Receptor Expression in Male and Female Rats: Raymond, J., Morin, A., et al.; Nutrients 16, (2024), Abstract
- Maternal high-fat or low-protein diets promote autism-related behavior and altered social behavior within groups in offspring male mice: Zilkha, N., Chuartzman, S. G., et al.; Sci. Rep. 14, 19227 (2024), Abstract
- Metabolic and behavioral alterations associated with viral vector-mediated toxicity in the paraventricular hypothalamic nucleus: Savani, R., Park, E., et al.; Biosci. Rep. 44, BSR20231846 (2024), Abstract
- Moving beyond the mean: an analysis of faecal corticosterone metabolites shows substantial variability both within and across white-tailed deer populations: Sutton, N. M., Suski, C., et al.; Conserv. Physiol. 12, coae062 (2024), Abstract
- Nutritional and physiological responses to dietary phosphorus levels and phytase in pullets and laying hens: Park, J., Heo, Y. J., et al.; Poult. Sci. 103, 103886 (2024), Abstract
- Olfactory stimulation with multiple odorants prevents stress-induced cognitive and psychological alterations: Bandiera, B., Natale, F., et al.; Brain Commun. 6, fcae390 (2024), Abstract
- Physiological and behavioral contagion/buffering effects of chronic unpredictable stress in a socially enriched environment: A preliminary study: Eraslan, E., Castelhano-Carlos, M. J., et al.; Neurobiol. Stress 30, 100635 (2024), Abstract
- Physiological state matching in a pair bonded poison frog: Nowicki, J. P., Rodriguez, C., et al.; R. Soc. Open Sci. 11, 240744 (2024), Abstract
- Platelet-derived LPA16:0 inhibits adult neurogenesis and stress resilience in anxiety disorder: Larrieu, T., Carron, C., et al.; bioRxiv , (2024)
- Postprandial exercise regulates tissue-specific triglyceride uptake through angiopoietin-like proteins: Liu, X., Zhang, Y., et al.; JCI Insight 9, (2024), Abstract
- Prenatal Acoustic Signals Influence Nestling Heat Shock Protein Response to Heat and Heterophil-to-Lymphocyte Ratio in a Desert Bird: Udino, E., Pessato, A., et al.; Int. J. Mol. Sci. 25, (2024), Abstract
- Research Note: Welfare and stress responses of broiler chickens raised in conventional and animal welfare-certified broiler farms: Kwon, B. Y., Lee, H. G., et al.; Poult. Sci. 103, 103402 (2024), Abstract
- Sex-dependent effects of early life stress on network and behavioral states: Scarpa, G., Antonoudiou, P., et al.; bioRxiv , (2024)
- Single Intranasal Administration of Ucn3 Affects the Development of PTSD Symptoms in an Animal Model: Tillinger, A., Zvozilova, A., et al.; Int. J. Mol. Sci. 25, (2024), Abstract
- Steroidogenic Factor-1 Regulation of Dorsomedial Ventromedial Hypothalamic Nucleus Ghrh Neuron Transmitter Marker and Estrogen Receptor Gene Expression in Male Rat: Sapkota, S., Roy, S. C., et al.; ASN Neuro 16, 2368382 (2024), Abstract
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- The effect of acute social isolation on neural molecular responses in components of the social decision-making network: Lopes, P. C., Chang, M., et al.; BMC Genomics 25, 771 (2024), Abstract
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- Thermoneutral Environment Improves Mouse Metabolism and Reduces Stress in Metabolic Cages: Seebeck, P., Villiger, P., et al.; Research Square , (2024)
- Unraveling the directional relationship of sleep and migraine-like pain: Vizin, R. C. L., Kopruszinski, C. M., et al.; Brain Commun. 6, fcae051 (2024), Abstract
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- Breeding zebra finches prioritize reproductive bout over self-maintenance under food restriction: Coutts, V. M., Pham, K., et al.; Biol. Open 13, bio060417 (2024), Abstract
- Effects of decreasing phosphorus concentrations in diets and phytase supplementation on growth performance, stress response, and intestinal health in broiler chickens: Lee, C., Kim, H. W., et al.; Poult. Sci. 103, 104418 (2024), Abstract
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- Prairie voles seek social contact with peer companions during immune challenge: Young, G. K., Chernyak, D., et al.; Horm. Behav. 166, 105653 (2024), Abstract
- Chemogenetic engagement of different GPCR signaling pathways segregates the orexigenic activity from the control of whole-body glucose metabolism by AGRP neurons: Espinal Abreu, V., Barnes, R., et al.; Mol. Metab. 91, 102079 (2024), Abstract
- Effects of Perch on Productivity, Welfare, and Physiological Indicators of Broiler Chickens Reared in Animal Welfare-Certificated Farms: Kwon, B. Y., Kim, S. T., et al.; Vet. Sci. 11, 614 (2024), Abstract
- Adolescent intermittent ethanol exposure enhances adult stress effects in male rats: K.L. Healey, et al.; Pharmacol. Biochem. Behav. 223, 173513 (2023), Abstract
- Cannabinoid Receptor 2 Blockade Prevents Anti-Depressive-like Effect of Cannabidiol Acid Methyl Ester in Female WKY Rats: D.H. Shoval, et al.; Int. J. Mol. Sci. 24, 3828 (2023), Abstract
- Chemically inducible split protein regulators for mammalian cells: E. Rihtar, et al.; Nat. Chem. Biol. 19, 64 (2023), Abstract
- Fermented Perilla frutescens Ameliorates Depression-like Behavior in Sleep-Deprivation-Induced Stress Model: H.J. Lee, et al.; Int. J. Mol. Sci. 24, 622 (2023), Abstract
- Integrating Reference Intervals into Chimpanzee Welfare Research: J.C. Whitham, et al.; Animals 13, 639 (2023), Abstract
- Single-day and multi-day exposure to orogastric gavages does not affect intestinal barrier function in mice: N. Hanning, et al.; Am. J. Physiol. Gastrointest. Liver Physiol. 324, G281 (2023), Abstract
- The resilience of adolescent male rats to acute stress-induced delayed anxiety is age-related and glucocorticoid release-dependent: R.C. Cardoso, et al.; Neuropharmacology 226, 109385 (2023), Abstract
- Vicarious Social Defeat Increases Conditioned Rewarding Effects of Cocaine and Ethanol Intake in Female Mice: F.R. González, et al.; Biomedicines 11, 502 (2023), Abstract
- Anti-depressive-like and cognitive impairment alleviation effects of Gastrodia elata Blume water extract is related to gut microbiome remodeling in Apo-/- mice exposed to unpredictable chronic mild stress: H.S. Huang, et al.; J. Ethnopharmacol. 302, 115872 (2023), Abstract
- Bank Voles Show More Impulsivity in IntelliCage Learning Tasks than Wood Mice: M. Jörimann, et al.; Neuroscience 510, 157 (2023), Abstract
- Behavioural traits related with resilience or vulnerability to the development of cocaine-induced conditioned place preference after exposure of female mice to vicarious social defeat: M.A. Martinez-Caballero, et al.; Prog. Neuropsychopharmacol. Biol. Psychiatry 130, 110912 (2023), Abstract
- Chronic stress induced loudness hyperacusis, sound avoidance and auditory cortex hyperactivity: S. Manohar, et al.; Hear. Res. 431, 108726 (2023), Abstract
- Circadian rhythm shifts and alcohol access in adolescence synergistically increase alcohol preference and intake in adulthood in male C57BL/6 mice: D. Gonzalez, et al.; Behav. Brain Res. 438, 114216 (2023), Abstract
- Early-Life Cooling Alters Later Corticosterone Response to Restraint in Prefledging Eastern Bluebirds (Sialia sialis) but Does Not Alter Adrenal Sensitivity to ACTH: S.E. Lynn & M.D. Kern; Physiol. Biochem. Zool. 96, 3 (2023), Abstract
- Effects of dietary protein levels on performance, nitrogen excretion, and odor emission of growing pullets and laying hens: Y.J. Heo, et al.; Poult. Sci. 102, 102798 (2023), Abstract
- Effects of Intermittent Fasting on Hypothalamus-Pituitary-Thyroid Axis, Palatable Food Intake, and Body Weight in Stressed Rats: C.G. Luna, et al.; Nutrients 15, 1164 (2023), Abstract
- Environmental enrichment accentuates glucose-induced feeding suppression and glial cell line-derived neurotrophic factor gene expression in the hypothalamus of mice: M.S. Aldhshan, et al.; Nutr. Neurosci. , (2023), Abstract
- Environmental signals perceived by the brain abate pro-metastatic monocytes by dampening glucocorticoids receptor signaling: M.M. Canali, et al.; Cancer Cell Int. 23, 15 (2023), Abstract
- Evaluation of an Extract Derived from the Seaweed Ascophyllum nodosum to Reduce the Negative Effects of Heat Stress on Broiler Growth and Stress Parameters: G.S. Archer, et al.; Animals 13, 259 (2023), Abstract
- Gut microbiota mediated inflammation, neuroendocrine and neurotrophic functions involved in the antidepressant-like effects of diosgenin in chronic restraint stress: J.J. Cui, et al.; J. Affect. Disord. 321, 242 (2023), Abstract
- Impact of host stress on the replication rate of Plasmodium take it easy to avoid malaria recurrences: R. Pigeault, et al.; Front. Ecol. Evol. , (2023), Application(s): Canary (bird) plasma, Full Text
- Implications of atrazine concentrations in drinking water from Ijebu-North, Southwest Nigeria on the hypothalamic-pituitary-adrenal axis: F. Owagboriaye, et al.; Drug Chem. Toxicol. , (2023), Abstract
- Individualized Housing Modifies the Immune-Endocrine System in CD1 Adult Male Mice: I.O. Saez, et al.; Animals 13, 1026 (2023), Abstract
- Inhibition of c-Jun in AgRP neurons increases stress-induced anxiety and colitis susceptibility: F. Jiao, et al.; Commun. Biol. 6, 50 (2023), Abstract
- Knockout of TSC2 in Nav1.8þ neurons predisposes to the onset of normal weight obesity: J.M. Brazill, et al.; Mol. Metab. 68, 101664 (2023), Abstract
- Neural basis for fasting activation of the hypothalamic-pituitary-adrenal axis: A.M. Douglass, et al.; Nature 620, 154 (2023), Abstract
- Ouabain Reverts CUS-Induced Disruption of the HPA Axis and Avoids Long-Term Spatial Memory Deficits: J.A. Leite, et al.; Biomedicines 11, 1177 (2023), Abstract
- Parity Increases Corticosterone Response To Restraint-induced Stress After Mild Blast Traumatic Brain Injury In Mice: S. Anisowicz; J. Endocr. Soc. 7 (Suppl 1), A150 (2023), Full Text
- Pregnancy rate and reproductive hormones in humpback whale blubber: Dominant form of progesterone differs during pregnancy: S. Atkinson, et al.; Gen. Comp. Endocrinol. 330, 114151 (2023), Abstract
- Protein-caloric restriction induced HPA axis activation and altered the milk composition imprint metabolism of weaned rat offspring: I.P. Martins, et al.; Nutrition 108, 111945 (2023), Abstract
- Sex-dependent role of orexin deficiency in feeding behavior and affective state of mice following intermittent access to a Western diet – Implications for binge-like eating behavior: N. Faesel, et al.; Physiol. Behav. 260, 114069 (2023), Abstract
- Synergistic antidepressant-like effect of n-3 polyunsaturated fatty acids and probiotics through the brain-gut axis in rats exposed to chronic mild stress: H. Cho, et al.; J. Nutr. Biochem. 116, 109326 (2023), Abstract
- The role of sociability in social instability stress: Behavioral, neuroendocrine and monoaminergic effects: A.D. Solinska, et al.; Physiol. Behav. 270, 114306 (2023), Abstract
- Unpredictable fasting transiently alters corticosterone and feeding behavior but not body mass or later HPA axis function in zebra finches (Taeniopygia guttata): S.E. Lynn, et al.; Comp. Biochem. Physiol. A Mol. Integr. Physiol. 281, 111434 (2023), Abstract
- Urbanization and maternal hormone transfer: Endocrine and morphological phenotypes across ontogenetic stages: J.J. Heppner, et al.; Gen. Comp. Endocrinol. 333, 114166 (2023), Abstract
- CerS6-dependent ceramide synthesis in hypothalamic neurons promotes ER/mitochondrial stress and impairs glucose homeostasis in obese mice: P. Hammerschmidt, et al.; Nat. Commun. 14, 7824 (2023), Abstract
- Corticosterone and immune responses to dehydration in squamate reptiles: K.T. Moeller, et al.; J. Exp. Biol. 225, jeb246257 (2023), Abstract
- Stress regulates Alzheimer’s disease progression via selective enrichment of CD8+ T cells: Y. Feng, et al.; Cell Rep. 42, 113313 (2023), Abstract
- A comparative study on feeding timing and additive types of broilers in a high-temperature environment: Son, J., Lee, W. D., et al.; J. Anim. Sci. 101, (2023), Abstract
- A parabrachial to hypothalamic pathway mediates defensive behavior: Wang, F., Chen, Y., et al.; Elife 12, (2023), Abstract
- A sex-specific thermogenic neurocircuit induced by predator smell recruiting cholecystokinin neurons in the dorsomedial hypothalamus: Jovanovic, P., Pool, A. H., et al.; Nat. Commun. 14, 4937 (2023), Abstract
- A small-molecule degrader of TET3 as treatment for anorexia nervosa in an animal model: Lv, H., Catarino, J. S., et al.; PNAS 120, e2300015120 (2023), Abstract
- Adrenal-Specific KO of the Circadian Clock Protein BMAL1 Alters Blood Pressure Rhythm and Timing of Eating Behavior: Costello, H. M., Crislip, G. R., et al.; Function (Oxf.) 4, zqad001 (2023), Abstract
- Akkermansia muciniphila supplementation improves glucose tolerance in intestinal Ffar4 knockout mice during the daily light to dark transition: Wang, Z., Cui, S., et al.; mSystems 8, e0057323 (2023), Abstract
- Analytical Validation and Assessment of Baseline Fecal Glucocorticoid Metabolites in Northern Sea Otters (Enhydra lutris kenyoni) in Human Care: Olsen, A. Y., Smith, A., et al.; Animals (Basel) 13, (2023), Abstract
- Anoctamin 4 channel currents activate glucose-inhibited neurons in the mouse ventromedial hypothalamus during hypoglycemia: Tu, L., Bean, J. C., et al.; J. Clin. Invest. 133, (2023), Abstract
- Automated Sleep Deprivation Setup Using a Shaking Platform in Mice: Bian, W. J., de Lecea, L., et al.; Bio Protoc. 13, e4620 (2023), Abstract
- Chronic HDM exposure shows time-of-day and sex-based differences in inflammatory response associated with lung circadian clock disruption: Srinivasan, A., Giri, A., et al.; iScience 26, 107580 (2023), Abstract
- CRF release from a unique subpopulation of accumbal neurons constrains action-outcome acquisition in reward learning: Eckenwiler, E. A., Ingebretson, A. E., et al.; bioRxiv , (2023)
- Diazepam Binding Inhibitor Control of Eu- and Hypoglycemic Patterns of Ventromedial Hypothalamic Nucleus Glucose-Regulatory Signaling: Roy, S. C., Sapkota, S., et al.; ASN Neuro 15, 17590914231214116 (2023), Abstract
- Differential G Protein-Coupled Estrogen Receptor-1 Regulation of Counter-Regulatory Transmitter Marker and 5′-AMP-Activated Protein Kinase Expression in Ventrolateral versus Dorsomedial Ventromedial Hypothalamic Nucleus: Bheemanapally, K., Briski, K. P., et al.; Neuroendocrinology 114, 25 (2023), Abstract
- Early-life obesogenic environment integrates immunometabolic and epigenetic signatures governing neuroinflammation: Ontiveros-Angel, P., Vega-Torres, J. D., et al.; bioRxiv , (2023)
- Effect of dietary glycine supplementation on productive performance, egg quality, stress response, and fatty liver incidence in laying hens raised under heat stress conditions: Nam, J. H., Han, G. P., et al.; Poult. Sci. 102, 103101 (2023), Abstract
- Effects of Ventromedial Hypothalamic Nucleus (VMN) Aromatase Gene Knockdown on VMN Glycogen Metabolism and Glucoregulatory Neurotransmission: Briski, K. P., Mahmood, A. S. M. H., et al.; Biology (Basel) 12, (2023), Abstract
- Estrous Cycle Mediates Midbrain Neuron Excitability Altering Social Behavior upon Stress: Shanley, M. R., Miura, Y., et al.; J. Neurosci. 43, 736 (2023), Abstract
- G protein-coupled lactate receptor GPR81 control of ventrolateral ventromedial hypothalamic nucleus glucoregulatory neurotransmitter and 5′-AMP-activated protein kinase expression: Roy, S. C., Napit, P. R., et al.; Am. J. Physiol. Regul. Integr. Comp. Physiol. 324, R20 (2023), Abstract
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- Effect of Providing Environmental Enrichment into Aviary House on the Welfare of Laying Hens: Son, J., Lee, W. D., et al.; Animals (Basel) 12, (2022), Abstract
- Effect of stocking density and vitamin E or zinc supplementation on growth, physiology, gene expression, and economic efficiency of growing broiler chicks: Shehata, S. F., Baloza, S. H., et al.; Trop. Anim. Health Prod. 54, 403 (2022), Abstract
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- Effects of Stocking Density on Growth Performance, Antioxidant Status, and Meat Quality of Finisher Broiler Chickens under High Temperature: Son, J., Kim, H. J., et al.; Antioxidants (Basel) 11, (2022), Abstract
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- Inhibition of Hippocampal Neurogenesis Starting in Adolescence Increases Anxiodepressive Behaviors Amid Stress: Larivee, R., Johnson, N., et al.; Front. Behav. Neurosci. 16, 940125 (2022), Abstract
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- Bifidobacterium longum counters the effects of obesity: Partial successful translation from rodent to human: Schellekens, H., Torres-Fuentes, C., et al.; EBioMedicine 63, 103176 (2021), Abstract
- Changes in Affective Behavior and Oxidative Stress after Binge Alcohol in Male and Female Rats: Cortez, I., Brocardo, P. S., et al.; Brain Sci. 11, (2021), Abstract
- Changes in the Orexin System in Rats Exhibiting Learned Helplessness Behaviors: Hsu, C. W., Wang, S., et al.; Brain Sci. 11, (2021), Abstract
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- Co-treatment With the Herbal Medicine SIP3 and Donepezil Improves Memory and Depression in the Mouse Model of Alzheimer’s Disease: Liu, Q. F., Choi, H., et al.; Research Square , (2021)
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- Early postnatal allergic airway inflammation induces dystrophic microglia leading to excitatory postsynaptic surplus and autism-like behavior: Saitoh, B. Y., Tanaka, E., et al.; Brain Behav. Immun. 95, 362 (2021), Abstract
- Effect of contact incubation on stress, behavior and body composition in the precocial Red jungle fowl: Henriksen, R., Holm, A. S., et al.; Horm. Behav. 128, 104892 (2021), Abstract
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- Effects of plant-derived isoquinoline alkaloids on growth performance and intestinal function of broiler chickens under heat stress: Kikusato, M., Xue, G., et al.; Poult. Sci. 100, 957 (2021), Abstract
- Electro-Acupuncture Attenuates Chronic Stress Responses via Up-Regulated Central NPY and GABA A Receptors in Rats: Yang, Y., Yu, H., et al.; Front. Neurosci. 14, 629003 (2021), Abstract
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- The Effect of Early Life Stress on Emotional Behaviors in GPR37KO Mice: Veenit, V., Zhang, X., et al.; Int. J. Mol. Sci. 23, (2021), Abstract
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- The Impact of Temperature and Humidity on the Performance and Physiology of Laying Hens: D. Kim, et al.; Animals 11, 56 (2020), Abstract
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- Prebiotic administration modulates gut microbiota and faecal short-chain fatty acid concentrations but does not prevent chronic intermittent hypoxia-induced apnoea and hypertension in adult rats: K.M. O’Connor, et al.; EBioMedicine 59, 102968 (2020), Abstract — Full Text
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- Adolescent Vulnerability to Heightened Emotional Reactivity and Anxiety After Brief Exposure to an Obesogenic Diet: J.D. Vega-Torres, et al.; Front. Neurosci. 14, 562 (2020), Abstract — Full Text
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- Adolescent sleep is critical for the developmental shaping of social novelty preference: Bian, W., de Lecea, L., et al.; bioRxiv , (2020)
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- Effects of dietary corticosterone on the central adenosine monophosphate-activated protein kinase (AMPK) signaling pathway in broiler chickens: Hu, X., Cai, Y., et al.; J. Anim. Sci. 98, (2020), Abstract
- Effects of Intracerebroventricular Glycogen Phosphorylase Inhibitor CP-316,819 Infusion on Hypothalamic Glycogen Content and Metabolic Neuron AMPK Activity and Neurotransmitter Expression in Male Rat: Ibrahim, M. M. H., Bheemanapally, K., et al.; J. Mol. Neurosci. 70, 647 (2020), Abstract
- Effects of putative stressors and adrenocorticotropic hormone on plasma concentrations of corticosterone in market-weight male turkeys: Scanes, C. G., Hurst, K., et al.; Poult. Sci. 99, 1156 (2020), Abstract
- Effects of supplementing yeast fermentate in the feed or drinking water on stress susceptibility, plasma chemistry, cytokine levels, antioxidant status, and stress- and immune-related gene expression of broiler chickens: Nelson, J. R., Sobotik, E. B., et al.; Poult. Sci. 99, 3312 (2020), Abstract
- Effects of Ultraviolet Light Supplementation on Pekin Duck Production, Behavior, and Welfare: House, G. M., Sobotik, E. B., et al.; Animals (Basel) 10, (2020), Abstract
- Effects of Xiaoyaosan on Depressive-Like Behaviors in Rats With Chronic Unpredictable Mild Stress Through HPA Axis Induced Astrocytic Activities: Song, M., Zhang, J., et al.; Front. Psychiatry 11, 545823 (2020), Abstract
- Electrostimulation of the carotid sinus nerve in mice attenuates inflammation via glucocorticoid receptor on myeloid immune cells: Falvey, A., Duprat, F., et al.; J. Neuroinflammation 17, 368 (2020), Abstract
- Environmental influences on placental programming and offspring outcomes following maternal immune activation: Núñez Estevez, K. J., Rondón-Ortiz, A. N., et al.; Brain Behav. Immun. 83, 44 (2020), Abstract
- FKBP5 and early life stress affect the hippocampus by an age-dependent mechanism: Criado-Marrero, M., Smith, T. M., et al.; Brain Behav. Immun. Health 9, 100143 (2020), Abstract
- Gut Microbiota-Induced Changes in β-Hydroxybutyrate Metabolism Are Linked to Altered Sociability and Depression in Alcohol Use Disorder: Leclercq, S., Le Roy, T., et al.; Cell Rep. 33, 108238 (2020), Abstract
- Heat Stress Causes Immune Abnormalities via Massive Damage to Effect Proliferation and Differentiation of Lymphocytes in Broiler Chickens: Hirakawa, R., Nurjanah, S., et al.; Front. Vet. Sci. 7, 46 (2020), Abstract
- High Salt Intake Lowers Behavioral Inhibition: Gilman, T. L., George, C. M., et al.; Front. Behav. Neurosci. 13, 271 (2020), Abstract
- High Temperature With Low Humidity or Vice Versa Does Not Affect Performance and Physiology of Laying Hens: Kim, D., Lee, Y., et al.; Preprints.org , (2020)
- Hippocampal µ-opioid receptors on GABAergic neurons mediate stress-induced impairment of memory retrieval: Shi, M. M., Fan, K. M., et al.; Mol. Psychiatry 25, 977 (2020), Abstract
- Identification of ALK in Thinness: Orthofer, M., Valsesia, A., et al.; Cell 181, 1246 (2020), Abstract
- Impact of caudal hindbrain glycogen metabolism on A2 noradrenergic neuron AMPK activation and ventromedial hypothalamic nucleus norepinephrine activity and glucoregulatory neurotransmitter marker protein expression: Alshamrani, A. A., Bheemanapally, K., et al.; Neuropeptides 82, 102055 (2020), Abstract
- Interactions between pyridostigmine bromide and stress on glutamatergic neurochemistry: Insights from a rat model of Gulf War Illness: Macht, V. A., Woodruff, J. L., et al.; Neurobiol. Stress 12, 100210 (2020), Abstract
- Light emitting diode (LED) color and broiler growth: effect of supplementing blue/green LED to white LED light on broiler growth, stress, and welfare: Nelson, J. R., Bray, J. L., et al.; Poult. Sci. 99, 3519 (2020), Abstract
- Lingering Effects of Prenatal Alcohol Exposure on Basal and Ethanol-Evoked Expression of Inflammatory-Related Genes in the CNS of Adolescent and Adult Rats: Doremus-Fitzwater, T. L., Youngentob, S. L., et al.; Front. Behav. Neurosci. 14, 82 (2020), Abstract
- Microglia depletion prior to lipopolysaccharide and paraquat treatment differentially modulates behavioral and neuronal outcomes in wild type and G2019S LRRK2 knock-in mice: Dwyer, Z., Rudyk, C., et al.; Brain Behav. Immun. Health 5, 100079 (2020), Abstract
- Mitochondrial gene signature in the prefrontal cortex for differential susceptibility to chronic stress: Weger, M., Alpern, D., et al.; Sci. Rep. 10, 18308 (2020), Abstract
- Neuroinflammation-Associated Aspecific Manipulation of Mouse Predator Fear by Toxoplasma gondii: Boillat, M., Hammoudi, P. M., et al.; Cell Rep. 30, 320 (2020), Abstract
- Optogenetic stimulation of the liver-projecting melanocortinergic pathway promotes hepatic glucose production: Kwon, E., Joung, H. Y., et al.; Nat. Commun. 11, 6295 (2020), Abstract
- Origin and Function of Stress-Induced IL-6 in Murine Models: Qing, H., Desrouleaux, R., et al.; Cell 182, 372 (2020), Abstract
- Paternal morphine self-administration produces object recognition memory deficits in female, but not male offspring: Ellis, A. S., Toussaint, A. B., et al.; Psychopharmacology (Berl.) 237, 1209 (2020), Abstract
- Physiological and behavioral responses to observing a sibling experience a direct stressor in prairie voles: Wardwell, J., Watanasriyakul, W. T., et al.; Stress 23, 444 (2020), Abstract
- Potential Involvement of Adiponectin Signaling in Regulating Physical Exercise-Elicited Hippocampal Neurogenesis and Dendritic Morphology in Stressed Mice: Wang, P., Liang, Y., et al.; Front. Cell. Neurosci. 14, 189 (2020), Abstract
- Prenatal metyrapone treatment modulates neonatal cerebrovascular structure, function, and vulnerability to mild hypoxic-ischemic injury: Franco, P. N., Durrant, L. M., et al.; Am. J. Physiol. Regul. Integr. Comp. Physiol. 318, R1 (2020), Abstract
- Rats Lacking Dopamine Transporter Display Increased Vulnerability and Aberrant Autonomic Response to Acute Stress: Illiano, P., Bigford, G. E., et al.; Biomolecules 10, (2020), Abstract
- Relative adrenal insufficiency is a risk factor and an endotype of sepsis – A proof of concept study to support a precision medicine approach for glucocorticoid sepsis therapy: Wu, C., Guo, L., et al.; bioRxiv , (2020)
- Response of Liver Metabolic Pathways to Ketogenic Diet and Exercise Are Not Additive: Huang, T. Y., Goldsmith, F. R., et al.; Med. Sci. Sports Exerc. 52, 37 (2020), Abstract
- Sensitized corticosterone responses do not mediate the enhanced fear memories in chronically stressed rats: Kulp, A. C., Lowden, B. M., et al.; Behav. Brain Res. 382, 112480 (2020), Abstract
- Sex differences in hypothalamic-pituitary-adrenal axis regulation after chronic unpredictable stress: Palumbo, M. C., Dominguez, S., et al.; Brain Behav. 10, e01586 (2020), Abstract
- Sex-specific brain erythropoietin regulation of mouse metabolism and hypothalamic inflammation: Dey, S., Cui, Z., et al.; JCI Insight 5, (2020), Abstract
- Sleep Disruption Exacerbates and Prolongs the Inflammatory Response to Traumatic Brain Injury: Tapp, Z. M., Kumar, J. E., et al.; J. Neurotrauma 37, 1829 (2020), Abstract
- SR-BI (Scavenger Receptor BI), Not LDL (Low-Density Lipoprotein) Receptor, Mediates Adrenal Stress Response-Brief Report: Ito, M., Ye, X., et al.; Arterioscler. Thromb. Vasc. Biol. 40, 1830 (2020), Abstract
- Supplementation of a water-soluble zinc-AA complex to reduce stress in broilers, pullets, and layers1: Nelson, J. R., Sobotik, E. B., et al.; J. Anim. Sci. 98, (2020), Abstract
- The enduring effects of early-life stress on the microbiota-gut-brain axis are buffered by dietary supplementation with milk fat globule membrane and a prebiotic blend: O’Mahony, S. M., McVey Neufeld, K. A., et al.; Eur. J. Neurosci. 51, 1042 (2020), Abstract
- The Relevance of Thimet Oligopeptidase in the Regulation of Energy Metabolism and Diet-Induced Obesity: Gewehr, M. C. F., Teixeira, A. A. S., et al.; Biomolecules 10, (2020), Abstract
- Therapeutic effects of anodal transcranial direct current stimulation in a rat model of ADHD: Jung, D. H., Ahn, S. M., et al.; Elife 9, (2020), Abstract
- Therapeutic efficacy of environmental enrichment on behavioral, endocrine, and synaptic alterations in an animal model of maternal immune activation: Zhao, X., Rondón-Ortiz, A. N., et al.; Brain Behav. Immun. Health 3, (2020), Abstract
- Xiaoyaosan Ameliorates Chronic Immobilization Stress-Induced Depression-Like Behaviors and Anorexia in Rats: The Role of the Nesfatin-1-Oxytocin-Proopiomelanocortin Neural Pathway in the Hypothalamus: Ma, Q., Li, X., et al.; Front. Psychiatry 10, 910 (2020), Abstract
- The adaptive immune and stress responses of adult female CD1 mice following exposure to a viral mimetic: R. Sharma, et al.; Immunol. Lett. 208, 30 (2019), Abstract
- Acute maternal separation potentiates the gene expression and corticosterone response induced by inflammation: J. Zajdel, et al.; Brain Behav. Immun. 77, 141 (2019), Abstract
- On the role of corticosterone in behavioral disorders, microbiota composition alteration and neuroimmune response in adult male mice subjected to maternal separation stress: H. Amini-Khoei, et al.; Int. Immunopharmacol. 66, 242 (2019), Abstract
- Cochlear Glucocorticoid Receptor and Serum Corticosterone Expression in a Rodent Model of Noise-induced Hearing Loss: Comparison of Timing of Dexamethasone Administration: S.H. Lee, et al.; Sci. Rep. 9, 12646 (2019), Abstract — Full Text
- The glucocorticoid receptor in brown adipocytes is dispensable for the systemic control of energy homeostasis through brown adipose tissue: C. Glantschnig, et al.; EMBO Rep. 20, e48552 (2019), Abstract — Full Text
- Corticosterone-Mediated Body Weight Loss Is an Important Catabolic Process for Poststroke Immunity and Survival: J. Yang, et al.; Stroke 50, 2539 (2019), Abstract
- Effects of high fat diet and chronic circadian challenge on glucocorticoid regulation in C57BL/6J mice: H.S. Appiakannan, et al.; Physiol. Behav. 204, 100 (2019), Abstract
- Sex differences in binge-like EtOH drinking, corticotropin-releasing hormone and corticosterone: effects of β-endorphin: T.B. Nentwig, et al.; Addict. Biol. 24, 447 (2019), Abstract — Full Text
- Stress-related over-enhancement of the hypothalamic-pituitary-adrenal axis causes experimental neurolathyrism in rats: K. Minagawa, et al.; Environ. Toxicol. Pharmacol. 72, 103245 (2019), Abstract
- Cortisol is the predominant glucocorticoid in the giant paedomorphic hellbender salamander (Cryptobranchus alleganiensis): W.A. Hopkins, et al.; Gen. Comp. Endocrinol. 285, 113267 (2019), Abstract
- Fear-based Aggression and Its Relationship to Corticosterone Responsiveness in Three Species of Python: J.A. Brashears, et al.; Gen. Comp. Endocrinol. 289, 113374 (2019), Abstract
- Effects of Environmental Enrichment in Maternally Separated Rats: Age and Sex-Specific Outcomes: R. Doreste, et al.; Front. Behav. Neurosci. 13, 198 (2019), Abstract
- Physical Activity Reduces Epilepsy Incidence: a Retrospective Cohort Study in Swedish Cross-Country Skiers and an Experimental Study in Seizure-Prone Synapsin II Knockout Mice: M. Ahl, et al.; Sports Med. Open 5, 52 (2019), Abstract
- Oxidative stress and mitochondrial responses to stress exposure suggest that king penguins are naturally equipped to resist stress: A. Stier, et al.; Sci. Rep. 9, 8545 (2019), Application(s): Penguin Plasma, Abstract — Full Text
- Noise-induced hearing loss alters hippocampal glucocorticoid receptor expression in rats: S.H. Hayes, et al.; Hear Res. 379, 43 (2019), Application(s): Rat plasma, Abstract
- Circadian variation in pulmonary inflammatory responses is independent of rhythmic glucocorticoid signaling in airway epithelial cells: L.M. Ince, et al.; FASEB J. 33, 126 (2019), Application(s): ELISA using mouse serum, Abstract — Full Text
- Constitutive differences in glucocorticoid responsiveness are related to divergent spatial information processing abilities: D. Huzard, et al.; Stress 12, 1 (2019), Application(s): ELISA using rat plasma, Abstract
- Deficiency of the immunoproteasome subunit β5i/LMP7 supports the anxiogenic effects of mild stress and facilitates cued fear memory in mice: X. Gorny, et al.; Brain Behav. Immun. 80, 35 (2019), Application(s): ELISA using mouse plasma, Abstract
- Effects of 50 Hz magnetic fields on circadian rhythm control in mice: L. Lundberg, et al.; Bioelectromagnetics 40, 250 (2019), Application(s): ELISA using mouse serum, Abstract — Full Text
- Effects of ecologically relevant concentrations of Boral® 500 SC, Glifosato® Biocarb, and a blend of both herbicides on markers of metabolism, stress, and nutritional condition factors in bullfrog tadpoles: A.L.L. Wilkens, et al.; Environ. Sci. Pollut. Res. Int. 26, 23242 (2019), Application(s): ELISA using bullfrog tadpoles, Abstract
- Examining the effects of chronic selenium exposure on traditionally used stress parameters in juvenile American alligators (Alligator mississippiensis): J.W. Finger, et al.; Arch. Environ. Contam. Toxicol. 77, 14 (2019), Application(s): ELISA using alligator plasma, Abstract
- Glucocorticoid-induced obesity develops independently of UCP1: I.H.N. Luijten, et al.; Cell Rep. 27, 1686 (2019), Application(s): ELISA using mouse serum, Abstract
- Hindbrain dorsal vagal complex AMPK controls hypothalamic gluco-regulatory transmitter and counter-regulatory hormone responses to hypoglycemia: S.K. Mandal, et al.; Brain Res. Bull. 144, 171 (2019), Application(s): ELISA using rat plasma, Abstract
- Hindbrain estrogen receptor regulation of ventromedial hypothalamic glycogen metabolism and glucoregulatory transmitter expression in the hypoglycemic male rat: M.H. Ali, et al.; Neuroscience 409, 253 (2019), Application(s): ELISA using rat plasma, Abstract
- Interventions after acute stress prevent its delayed effects on the amygdala: P. Chakraborty & S. Chattarji; Neurobiol. Stress 10, 100168 (2019), Application(s): ELISA using rat serum, Abstract — Full Text
- Chronic stress induces hypersensitivity of murine gastric vagal afferents: H. Li, et al.; Neurogastroenterol. Motil. 31, e13669 (2019), Application(s): ELISA using mouse plasma, Abstract
- Chronic exposure to inorganic mercury alters stress responses in male prairie voles (Microtus ochrogaster): M. Soto, et al.; Horm. Behav. 109, 53 (2019), Application(s): ELISA using vole plasma, Abstract
- High dose of dexamethasone protects against EAE-induced motor deficits but impairs learning/memory in C57BL/6 mice: N. Dos Santos, et al.; Sci. Rep. 9, 6673 (2019), Abstract — Full Text
- No short-term physiological costs of offspring care in a cooperatively breeding bird: S. Guindre-Parker & D.R. Rubenstein; J. Exp. Biol. 221, jeb186569 (2019), Abstract — Full Text
- Mammary tumors compromise time-of-day differences in hypothalamic gene expression and circadian behavior and physiology in mice: K.A. Sullivan, et al.; Brain Behav. Immun. 80, 805 (2019), Abstract
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Specific Protocol
Suggested Protocol for Small Volumes of Serum/Plasma Samples
- Let all solutions come to room temp before use.
- Aliquot 10µl of each sample into microfuge tube.
- Make 1ml 1:100 Steroid Displacement Reagent (SDR) solution (immediately before use) in deionized water or PBS (not assay buffer)
- Add 10µl 1:100 SDR to each sample tube.
- Vortex, let stand >5 minutes before diluting with EIA buffer.
- Add 380µl EIA assay buffer to each plasma tube, vortex.
Final dilution is ~1:40 (This final dilution may not be appropriate for every sample; thus, optimal dilution must be determined by each end user for their experimental sample group.)
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