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Compound 115-7c

ENZ-CHM471

  • ENZ-CHM471-0025   —   25 mg
    $764.00

Acts as an artificial co-chaperone for HSP70. The activity of compound 115-7c mirrors those of HSP40 stimulating the ATPase and protein-folding activities of prokaryotic HSP70. Increases tau levels in cell lines overexpressing tau. Induces solubilization of polyglutamine and exacerbates polyQ-mediated toxicity. An important probe for understanding HSP70 functions.

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Regulatory Status

RUO – Research Use Only