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Collagen I, rat tail

ALX-522-435

26 citations

  • ALX-522-435-0020   —   20 mg
    $90.00
  • ALX-522-435-0100   —   100 mg
    $212.00
  • New formulation enhances gelling over a larger concentration range.

Collagen is the main component in connective tissue and helps to provide support for tissues. It is made up of several classes, with Type 1 collagen being the most common. Type 1 collagen has a herterotrimeric triple helical structure made up of two alpha-1(I) and one alpha-2(I) chains that form into elongated fibrils which are extremely strong. These fibrils can be found in skin, tendons, ligaments, and other connective tissues. Type 1 collagen has been shown to be useful as a substrate that promotes cell growth and proliferation. Under acidic conditions the protein is soluble, however by raising the temperature and pH the solution forms into a solid gel that can be useful for cellular studies. It can also be dried to form a thin layer on solid surfaces such as plates, slides, or coverslips to aid in cell attachment.

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Regulatory Status

RUO – Research Use Only