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CNQX . disodium salt

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AMPA/kainate receptor antagonist

Water soluble, potent competitive kainate/quisqualate (non-NMDA) receptor antagonist. More soluble form of CNQX (Prod. No. ALX-550-042).

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Alternative Name	6-Cyano-7-nitroquinoxaline-2,3-dione . 2Na
Appearance	Rust red solid.
CAS	115066-14-3 (non-salt)
Couple Target	AMPA receptor, Kainate receptor
Couple Type	Inhibitor, Ligand
Formula	C₉H₂N₄O₄ . 2Na
MW	230.1 . 46.0
Purity	≥98% (TLC)
Solubility	Soluble in water (5mg/ml).

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Protect from light.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Differential effects of the excitatory amino acid antagonists, 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) and 3-((+-)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP), on spinal reflex activity in mice: L. Turski, et al.; Neurosci. Lett. 113, 66 (1990), Abstract
Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists: T. Honoré, et al.; Science 241, 701 (1988), Abstract