Chromogranin A polyclonal antibody

Chromogranin A (CgA) is a prohormone which is proteolytically processed in neurons prior to axonal transport. The differential expression of chromogranin A fragments in neuronal populations suggests distinct functional roles for each CgA-derived peptide. Immunohistochemical localization of CgA has been used as a marker for the identification and prognostic assessment of neuroendocrine tumours and CgA has also been reported to be a component of senile plaques in the brains of demented individuals.