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Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2 (COX-2) with an IC50 of 40 nM. It is commonly used to treat pain and inflammation associated with conditions like osteoarthritis and rheumatoid arthritis. Celecoxib is known for its lower risk of gastrointestinal side effects compared to non-selective NSAIDs.
Key features and applications include:
- Selective COX-2 Inhibition: Targets the COX-2 enzyme specifically, reducing pain and inflammation with fewer gastrointestinal side effects compared to non-selective NSAIDs.
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RUO – Research Use Only |
|---|
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| CAS | 38966-21-1 |
|---|---|
| Couple Type | Inhibitor |
| Purity | ≥98% (TLC) |
| Alternative Name | (3R,4R)-4-[(3,4-Dimethoxyphenyl)methyl]dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2-(3H)-furanone |
|---|---|
| CAS | 7770-78-7 |
| Couple Type | Inhibitor |
| Purity | ≥97% (HPLC) |
| Alternative Name | (3R,4R)-4-[(3,4-Dimethoxyphenyl)methyl]-3-[[4-(β-D-glucopyranosyloxy)-3-methoxyphenyl]methyl]dihydro-2(3H)-furanone |
|---|---|
| CAS | 20362-31-6 |
| Couple Type | Inhibitor |
| Purity | ≥95% (HPLC) |
| Alternative Name | EGCG, (2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol 3-(3,4,5-trihydroxybenzoate) |
|---|---|
| CAS | 989-51-5 |
| Couple Type | Inhibitor |
| Purity | ≥98% (HPLC) |