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CD83 (human) monoclonal antibody (1G11)

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Application	Flow Cytometry, WB
Application Notes	NOT inhibitory to DC mediated T cell stimulation in mixed lymphocyte reactions.
Clone	1G11
Formulation	Liquid. In PBS containing 0.01% sodium azide.
Host	Rat
Immunogen	Recombinant human CD83 (extracellular domain).
Isotype	IgG1
Purity Detail	Protein G-affinity purified.
Species Reactivity	Human
Specificity	The binding affinity strongly increases after deglycosylation of mature DC.
UniProt ID	Q01151
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Regulatory Status	RUO – Research Use Only

Overexpression, purification, and biochemical characterization of the extracellular human CD83 domain and generation of monoclonal antibodies: M. Lechmann, et al.; Protein Exp. Purif. 24, 445 (2002), Abstract
The extracellular domain of CD83 inhibits dendritic cell-mediated T cell stimulation and binds to a ligand on dendritic cells: M. Lechmann, et al.; J. Exp. Med. 194, 1813 (2001), Abstract — Full Text

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