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CD40L (human) monoclonal antibody (blocking) (MK13A4)

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This antibody is covered by our Worry-Free Guarantee.

Alternative Name	CD154, gp39, TNFSF 5
Application	Flow Cytometry, FUNC
Application Notes	Functional Application: blocks binding of CD40L to its receptor CD40.
Clone	MK13A4
Formulation	Liquid. In PBS, pH 7.2-7.4.
Host	Mouse
Immunogen	Recombinant human CD40L (CD154).
Isotype	IgG1
Species Reactivity	Human
UniProt ID	P29965
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Handling	Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Long Term Storage	+4°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Platelets subvert antitumor efficacy of T cell-recruiting bispecific antibodies: Lutz, M. S., Klimovich, B., et al.; J. Immunother. Cancer 10, (2022), Abstract
Type 1-programmed dendritic cells drive antigen-specific latency reversal and immune elimination of persistent HIV-1: J. Kristoff, et al.; EBioMedicine 43, 295 (2019), Application(s): Block / Reactant(s) Human, Abstract
Cell enrichment-free massive ex-vivo expansion of peripheral CD20+ B cells via CD40-CD40L signals in non-human primates: J.S. Kim, et al.; Biochem. Biophys. Res. Commun. 473, 92 (2016), Application(s): Ex-vivo, cell culture, Abstract
Upregulation of the CD40/CD40 ligand dyad and platelet-monocyte aggregation in cigarette smokers: Harding, S. A., Sarma, J., et al.; Circulation 109, 1926 (2004), Abstract

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