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CBA is a selective blocker of TRPM4 channels with no activity at TRPM5, TRPM7, TRPM8, TRPV1, TRPV3, TRPV6 and a panel of other ion channels and receptors. Displays protective effects in murine experimental autoimmune encephalomyelitis and in a model of glutamate-induced neuronal degeneration. A highly useful tool for exploring the functions of TRPM4 in a variety of cell types.
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RUO – Research Use Only |
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