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CAT1H . hydrochloride

ALX-430-131

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Spin probe

Cyclic hydroxylamine spin probe for in vivo, intraperitoneal and intravenous injections. Lifetime of more than 4 hours in blood plasma, in cells and tissue. Allows quantitative measurements of extracellular O2^•– and quantification of intracellular O2^•– in cells and tissue samples and in vivo O2^•– detection.

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Product Details

Alternative Name	1-Hydroxy-2,2,6,6-tetramethylpiperidin-4-yl-trimethylammonium chloride . HCl
Appearance	Colorless crystalline solid.
Formula	C₁₂H₂₆N₂O . 2HCl
MW	214.4 . 72.9
Purity Detail	Paramagnetic impurities ≤0.01% (EPR).
Solubility	Soluble in water, methanol or 100% ethanol.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Protect from moisture.
Short Term Storage	+4°C
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Use of Electron Paramagnetic Resonance in Biological Samples at Ambient Temperature and 77 K: H.B. Eajaili, et al.; J. Vis. Exp. , e58461 (2019), Abstract
LRRC8A channels support TNFα-induced superoxide production by Nox1 which is required for receptor endocytosis: H. Choi, et al.; Free Radic. Biol. Med. 101, 413 (2016), Abstract
EPR detection of cellular and mitochondrial superoxide using cyclic hydroxylamines: S.I. Dikalov, et al.; Free Rad. Res. 45, 417 (2011), Abstract
Measurement of reactive oxygen species in cardiovascular studies: S. Dikalov, et al.; Hypertension 49, 717 (2007), Abstract
Role of the T cell in the genesis of angiotensin II induced hypertension and vascular dysfunction: T.J. Guzik, et al.; J. Exp. Med. 204, 2449 (2007), Abstract — Full Text
Mitochondrial redox cycling of mitoquinone leads to superoxide production and cellular apoptosis: A.K. Doughan & S.I. Dikalov; Antioxid. Redox Signal. 9, 1825 (2007), Abstract
Role of extracellular superoxide dismutase in hypertension: M.C. Gongora, et al.; Hypertension 48, 473 (2006), Abstract — Full Text

Last modified: May 29, 2024

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CAT1H . hydrochloride

ALX-430-131

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

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