Home Shop Castanospermine

Castanospermine

BML-S107

Datasheet
Manual
SDS
CofA

Already have an account?

Glucosidase inhibitor

Plant alkaloid. Potent inhibitor of α- and β-glucosidases. Exhibits antiviral properties. Inhibits thyroglobulin secretion. Antitumor activity. Inhibits protein glycosylation. Prevents angiogenesis.

Shipping: Available products typically ship within 24/48h, via priority shipping.

Do you need support? Contact Customer Service or Technical Support.

Online Account
Access or Create Your Account

Product Details

Appearance	White to off-white crystalline solid.
CAS	79831-76-8
Couple Target	Glucosidase, Glycosidase
Couple Type	Inhibitor
Formula	C₈H₁₅NO₄
MI	14: 1896
MW	189.2
Purity	≥95% (TLC)
Solubility	Soluble in water.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended. Stable for at least 1 year after receipt when stored at 4°C. Stock solutions are stable for for up to 3 months at -20°C.
Long Term Storage	+4°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Aberrant N-glycosylation in pathogenic variants of adenosine deaminase 2 underlying human ADA2 deficiency: Ehlers, L., Hombrouck, A., et al.; bioRxiv , (2023)
LMAN1 (ERGIC-53) is a potential carrier protein for matrix metalloproteinase-9 glycoprotein secretion: T. Duellman, et al.; Biochem. Biophys. Res. Commun. 464, 385 (2015), Application(s): Cell Culture, Abstract
Perturbation of free oligosaccharide trafficking in endoplasmic reticulum glucosidase I-deficient and castanospermine-treated cells.: C. Durrant & S.E. Moore; Biochem. J. 365, 239 (2002), Abstract
The alpha-glucosidase I inhibitor castanospermine alters endothelial cell glycosylation, prevents angiogenesis, and inhibits tumor growth.: R. Pili, et al.; Cancer Res. 55, 2920 (1995), Abstract
Antiviral activity and metabolism of the castanospermine derivative MDL 28,574, in cells infected with herpes simplex virus type 2.: S.P. Ahmed, et al.; BBRC 208, 267 (1995), Abstract
Effects of the anti-inflammatory compounds castanospermine, mannose-6- phosphate and fucoidan on allograft rejection and elicited peritoneal exudates.: M.R. Bartlett, et al.; Immunol. Cell Biol. 72, 367 (1994), Abstract
Simultaneous determination of sugar incorporation into glycosphingolipids and glycoproteins.: P. Paul, et al.; Anal. Biochem. 204, 265 (1992), Abstract
Castanospermine vs. its 6-O-butanoyl analog: a comparison of toxicity and antiviral activity in vitro and in vivo.: R.M. Ruprecht, et al.; J. Acquir. Immune Defic. Syndr. 4, 48 (1991), Abstract
Effects of deoxymannojirimycin and castanospermine on the polarized secretion of thyroglobulin.: J. Franc, et al.; Endocrinology 126, 1464 (1990), Abstract
Inhibition of v-fms-induced tumor growth in nude mice by castanospermine.: G.K. Ostrander, et al.; Cancer Res. 48, 1091 (1988), Abstract

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Datasheet

Certificate of Analysis

Please enter the lot number as featured on the product label

Lot No. :

SDS

Enzo Life Science provides GHS Compliant SDS

English (EU) SDS

If your language is not available please fill out the SDS request form

Your Cart

Your Cart

Castanospermine

BML-S107

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

Change Country

Tell us about You

Tell us about your paper

Tell us about You

Tell us about your project