Home Shop Caspase-9 (full-length) (human), (recombinant)

Caspase-9 (full-length) (human), (recombinant)

BML-SE240

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Binding of procaspase-9 to the apoptosome promotes autoprocessing to an active form of the enzyme which, like this recombinant preparation, consists of 35 kDa and 12 kDa subunits.

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Product Details

Alternative Name	ICE-LAP-6, Mch6
Concentration	500 U/µl
Formulation	Liquid. In 50 mM HEPES, pH 7.4, 100mM NaCl, 0.5% CHAPS, 1mM EDTA, 10% glycerol, 10mM DTT.
MW	35 + 12 kDa subunits
Purity	≥85% (SDS-PAGE)
Source	Produced in E. coli. Full length human caspase-9 (aa 1-416).
Specific Activity	One U=1 pmol/min at 30°C using Ac-LEHD-pNA (2 mM; Prod. No. ALX-260-081) as substrate.
UniProt ID	P55211

Handling & Storage

Long Term Storage	-80°C
Shipping	Dry Ice

Regulatory Status	RUO – Research Use Only

A Potent Inhibitor of Caspase‑8 Based on the IL-18 Tetrapeptide Sequence Reveals Shared Specificities between Inflammatory and Apoptotic Initiator Caspases: C.M. Bourne, et al.; bioRxiv , 02.23.639785 (2025), Abstract — Full Text