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Caspase-5 (human), (recombinant)

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Activity	100 U/µl
Alternative Name	ICH-3, Protease TY, ICErel-III
Formulation	Liquid. In 50mM HEPES, pH 7.4, 100mM NaCl, 0.5% CHAPS, 1mM EDTA, 10% glycerol, 10mM DTT.
MW	22 + 10 kDa
Purity	≥80% (SDS-PAGE)
Source	Produced in E. coli
Specific Activity	One U=1 pmol/min at 30°C using Ac-LEHD-pNA (200 µM; Prod. No. ALX-260-081) as substrate.
UniProt ID	P51878

Long Term Storage	-80°C
Shipping	Dry Ice

Regulatory Status	RUO – Research Use Only

A Potent Inhibitor of Caspase‑8 Based on the IL-18 Tetrapeptide Sequence Reveals Shared Specificities between Inflammatory and Apoptotic Initiator Caspases: C.M. Bourne, et al.; bioRxiv , 02.23.639785 (2025), Abstract — Full Text
The tetrapeptide sequence of IL-18 and IL-1β regulates their recruitment and activation by inflammatory caspases: Exconde, P. M., Hernandez-Chavez, C., et al.; Cell Rep. 42, 113581 (2023), Abstract

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