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Caspase-10 is an initiator caspase, highly homologous to caspase-8, a relationship that extends to the death effector domains (DEDs) of their proforms. Caspase-10 was reported to activate early in TRAIL-induced apoptosis and was found in association with the DR4 (TRAIL-R1) receptor complex in a thyroid carcinoma line.
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RUO – Research Use Only |
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