c[A(3′,5′)pA(3′,5′)pG(3′,5′)p] / cAAG
BLG-C361
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c[A(3′,5′)pA(3′,5′)pG(3′,5′)p] is a cyclic trinucleotide that was found to be biosynthesized by CD-NTase038 from the Enterobacter cloacae complex (strain UCI 50) (WP_032676400, also named EcCdnD02). While c[A(3′,5′)pA(3′,5′)pG(3′,5′)p] is not recognized by STING, it binds to the mammalian cyclic dinucleotide sensor RECON (REductase COntrolling NF-κB) (all data according to Whiteley et al., Nature, 567, 194 – 199 (2019)).
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