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c[A(2′,5′)pS-G(3′,5′)pS], isomer 1
BLG-C246
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c[A(2′,5′)pS-G(3′,5′)pS], isomer 1 (syn. 3’2′-cGAMPSS, isomer 1) is an isomeric di-thiophosphate derivative of the recently discovered nucleotide second messenger c[A(2′,5′)pG(3′,5′)p] (3’2′-cGAMP, Cat. No. C 238). The di-thiophosphate modifications are expected to render the compound resistant to degradation by 3’2′-cGAMP hydrolysing enzymes. c[A(2′,5′)pS-G(3′,5′)pS], isomer 2 is available as well (syn. 3’2′-cGAMPSS, isomer 2, Cat. No. C 247).
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| Regulatory Status |
RUO – Research Use Only |
|---|
Related Products
| Alternative Name | Cyclic (adenosine-(2’→5′)-monophosphate-guanosine-(3’→5′)-monophosphate) . sodium salt, 3′,5′-2′,5′-cGAMP |
|---|---|
| Couple Type | Modified nucleotides |
| Purity | > 98% HPLC |
| Alternative Name | 3’2′-cGAMPSS, isomer 2, 3′,5′-2′,5′-cGAMPSS, Cyclic (adenosine-(2’→5′)-monophosphorothioate-guanosine- (3’→5′-monophosphorothioate), isomer 2 . sodium salt |
|---|---|
| Purity | > 95% HPLC |