BMP-4 (human), (recombinant)

Bone morphogenetic protein 4 (BMP-4) is a member of the bone morphogenetic growth factor family (BMP) and functions as a critical component in the culture and differentiation of stem cells. Active BMP-4 forms a homodimer or a heterodimer with related BMPs. BMP-4 is integral for the differentiation of mesoderm and ectoderm from pluripotent stem cells (iPSCs and ESCs) in stem cell cultures. BMP-4 is also used in culturing cardiomyocytes, early hematopoietic cells, hepatocytes, bone, cartilage, adipocytes, and lung cells, as well as inhibiting early neuronal differentiation.