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Potent (AC50 = 0.111µM) and selective (over PKM1, PKR and PKL) activator of the tumor cell specific M2 isoform of pyruvate kinase (PKM2). Pyruvate kinase is a potential target for cancer chemotherapy. A useful new tool for altering aberrant glucose metabolism in cancer cells (Warburg effect).
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RUO – Research Use Only |
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