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BML-266

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SIRT inhibitor

Structurally novel SIRT2 inhibitor (IC₅₀=56.7µM).

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Alternative Name	1,4-Di[(4-hydroxyphenethyl)amino]-9,10-dihydroanthracene-9,10-dione
Appearance	Dark purple solid.
CAS	96969-83-4
Couple Target	SIRT, SIRT2
Couple Type	Inhibitor
Formula	C₃₀H₂₆N₂O₄
Identity	Determined by NMR.
MW	478.5
Purity	≥95% (TLC)
Solubility	Soluble in DMSO (25mg/ml).

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

N,N’-Bisbenzylidenebenzene-1,4-diamines and N,N’-Bisbenzylidenenaphthalene-1,4-diamines as Sirtuin Type 2 (SIRT2) Inhibitors: P.H. Kiviranta, et al.; J. Med. Chem. 49, 7907 (2006), Abstract

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