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Blasticidin S . hydrochloride

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Antibiotic

Antibiotic. Inhibitor of DNA and protein synthesis.

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Appearance	White to off-white powder.
CAS	3513-03-9
Formula	C₁₇H₂₆N₈O₅. HCl
MI	14: 1316
MW	422.4 . 36.5
Purity	≥98% (HPLC)
Solubility	Soluble in water; insoluble in organic solvents.
Source	Isolated from Streptomyces griseochromogenes.

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Protect from moisture.
Long Term Storage	+4°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Packaging cells for lentiviral vectors generated using the cumate and coumermycin gene induction systems and nanowell single-cell cloning: S. Broussau, et al.; Mol. Ther. Methods Clin. Dev. 8, 29 (2023), Abstract
A mutation in the kringle domain of human factor XII that causes autoinflammation, disturbs zymogen quiescence, and accelerates activation: Z.L.M. Hofman, et al.; J. Biol. Chem. 295, 363 (2020), Abstract — Full Text
Cloning of the blasticidin S deaminase gene (BSD) from Aspergillus terreus and its use as a selectable marker for Schizosaccharomyces pombe and Pyricularia oryzae: M. Kimura, et al.; Mol. Gen. Genet. 242, 121 (1994), Abstract
Blasticidin S deaminase gene from Aspergillus terreus (BSD): a new drug resistance gene for transfection of mammalian cells: M. Kimura, et al.; Biochim. Biophys. Acta 1219, 653 (1994), Abstract
Blasticidin S-resistance gene (bsr): a novel selectable marker for mammalian cells: M. Izumi, et al.; Exp. Cell Res. 197, 229 (1991), Abstract
The blasticidin S resistance gene (bsr) selectable in a single copy state in the Bacillus subtilis chromosome: M. Itaya, et al.; J. Biochem. 107, 799 (1990), Abstract
Cloning and characterization of the gene encoding a blasticidin S acetyltransferase from Streptoverticillum sp: J.A. Perez-Gonzalez, et al.; Gene 86, 129 (1990), Abstract
Blasticidin S, a new antibiotic: S. Takeuchi, et al.; J. Antibiot. (Tokyo) 11, 1 (1958), Abstract

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