Biotinylated K11-Linked Tetra-Ubiquitin (Phosphorylated)

K11-linked ubiquitination is traditionally associated with cell cycle regulation and proteasomal degradation. Phospho-ubiquitin chains represent a specialized class of polyubiquitin characterized by phosphorylation at Serine 65 and play a central role in mitophagy signaling pathways. K11 linkage appears to play an important role in cell cycle signaling, as it is associated with the anaphase promoting complex (APC).