Biotinylated K11-Linked Tetra-Ubiquitin

K11-linked ubiquitination is traditionally associated with cell cycle regulation and proteasomal degradation. Phospho-ubiquitin chains represent a specialized class of polyubiquitin characterized by phosphorylation at Serine 65 and play a central role in mitophagy signaling pathways. K11-linked ubiquitination is traditionally associated with cell cycle regulation and proteasomal degradation. K11 linkage appears to play an important role in cell cycle signaling, as it is associated with the anaphase promoting complex (APC).