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Bimatoprost

BML-RA121

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FP receptor agonist

Stable analog of PGF2α. Agonist at FP receptors (after in vivo hydrolysis to the free acid). It is an efficacious treatment for glaucoma. It also displays an unusual eye lash lengthening effect.

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Product Details

Alternative Name	(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-ethylhept-5-enamide
Appearance	White to off-white powder.
CAS	155206-00-1
Couple Target	Prostanoid receptor
Couple Type	Activator, Ligand
Formula	C₂₅H₃₇NO₄
MW	415.6
Purity	≥97%
Solubility	Soluble in DMSO (25mg/ml) or ethanol (25mg/ml).

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended. Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

A meta-analysis of topical prostaglandin analogs in the treatment of chronic angle-closure glaucoma: J.W. Cheng, et al.; J. Glaucoma 18, 652 (2009), Abstract
Role of prostaglandins and specific place in therapy of bimatoprost in the treatment of elevated intraocular pressure and ocular hypertension: A closer look at the agonist properties of bimatoprost and the prostamides: S.D. Smid; Clin. Ophthalmol. 3, 663 (2009), Abstract

Last modified: May 29, 2024

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Bimatoprost

BML-RA121

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Handling & Storage

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