
- Measures total and/or direct bilirubin in plasma, serum, urine, or cell and tissue lysates
- Detection sensitivity of 0.5mg/dL bilirubin
- Bilirubin standard curve included
Bilirubin, a byproduct of heme breakdown, can exist conjugated to glucuronic acid (direct) and as unconjugated (indirect). The unconjugated form is found in the blood bound to albumin and is transported to the liver. Bilirubin becomes conjugated to glucuronic acid in the liver, making it more soluble and allowing for excretion into bile. High levels of bilirubin have been correlated with jaundice and Gilbert’s syndrome while low levels have been associated with cardiovascular disease and diabetes mellitus.
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RUO – Research Use Only |
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