Home Shop Big Endothelin-1 (human) (1-38)

Big Endothelin-1 (human) (1-38)

ALX-152-001

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ALX-152-001-PC01 — 0.1 mg*

$147.00

Big Endothelin-1 (human) (1-38) quantity
ALX-152-001-PC05 — 0.5 mg*

$691.00

Big Endothelin-1 (human) (1-38) quantity
ALX-152-001-P001 — 1 mg*

$1,104.00

Big Endothelin-1 (human) (1-38) quantity

Endothelin-converting enzyme substrate

Biological precursor of endothelin 1. Cleaved to yield endothelin-1 via the activity of the endothelin-converting enzyme (ECE). Endothelins are endothelium-derived vasoconstrictor peptides.

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Product Details

Alternative Name	Big ET-1 (1-38)
Appearance	White to off-white powder.
CAS	121014-53-7
Formula	C₁₈₉H₂₈₂N₄₈O₅₆S₅
MW	4283.0
Purity	≥98% (HPLC)
Quantity	*Sold as net peptide weight.
Sequence	H-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-Val-Asn-Thr-Pro-Glu-His-Val-Val-Pro-Tyr-Gly-Leu-Gly-Ser-Pro-Arg-Ser-OH (Disulfide bonds between Cys¹-Cys¹⁵and Cys³-Cys¹¹)
Solubility	1mg/ml soluble in water; also soluble in 0.5% acetic acid.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Putative precursors of endothelin have less vasoconstrictor activity in vitro but a potent pressor effect in vivo: T. Kashiwabara, et al.; FEBS Lett. 247, 73 (1989), Abstract
Cloning and sequence analysis of cDNA encoding the precursor of a human endothelium-derived vasoconstrictor peptide, endothelin: identity of human and porcine endothelin: Y. Itoh, et al.; FEBS Lett. 231, 440 (1988), Abstract

Last modified: May 29, 2024

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Big Endothelin-1 (human) (1-38)

ALX-152-001

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

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