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Benserazide . HCl

BML-EI165

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Peripheral decarboxylase inhibitor

Peripheral decarboxylase inhibitor. Also inhibits tryptophan hydroxylase and tyrosine hydroxylase. Used with L-DOPA as a Parkinson’s disease therapeutic.

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Product Details

Appearance	Tan solid.
CAS	14919-77-8
Couple Target	Peripheral decarboxylase, Tryptophan hydroxylase, Tyrosine hydroxylase
Couple Type	Inhibitor
Formula	C₁₀H₁₅N₃O₅ . HCl
MW	293.7
Purity	≥98%
Solubility	Soluble in water. Almost insoluble in 100% ethanol, insoluble in acetone.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended. Product is subject to oxidation. Make solutions fresh daily. Store, as supplied, at room temperature for up to 1 year.
Handling	Protect from light.
Long Term Storage	Ambient
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

In vitro cardiac pharmacology of the new histamine H2-receptor agonist amthamine: comparisons with histamine and dimaprit: E. Poli et al.; Agents Actions 40, 44 (1993), Abstract
The new potent and selective histamine H2 receptor agonist amthamine as a tool to study gastric secretion: G. Coruzzi et al.; Naunyn Schmiedebergs Arch. Pharmacol. 348, 77 (1993), Abstract
Single-dose study of slow release preparation of levodopa and benserazide (Madopar HBS) in Parkinson’s disease: M.-H. Marion et al.; Adv. Neurol. 45, 493 (1987), Abstract
Astemizole. A review of its pharmacodynamic properties and therapeutic efficacy: D.M. Richards et al.; Drugs 28, 38 (1984), Abstract
In vitro and in vivo binding characteristics of a new long-acting histamine H1 antagonist, astemizole: P.M. Laduron et al.; Mol. Pharmacol. 21, 294 (1982), Abstract
Levodopa and decarboxylase inhibitors: a review of their clinical pharmacology and use in the treatment of parkinsonism: R.M. Pinder et al.; Drugs 11, 329 (1976), Abstract

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Benserazide . HCl

BML-EI165

Product Details

Handling & Storage

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