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Bax monoclonal antibody (4F11)

ADI-AAM-140

4 citations

  • ADI-AAM-140-E   —   100 µg
    $385.00

Bax is an appromimately 22 kDa pro-apoptotic protein belonging to the Bcl-2 family of proteins, which are characterized by the presence of at least one Bcl-2 homology (BH) domains. Bax normally resides in the cytoplasm, but following an apoptotic stimuli, Bax undergoes a conformational change and translocates to mitochondrial membranes where it inserts and mediates the release of cytochrome c. This activates caspase-3 and perpetuates the apoptotic cascade.

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Regulatory Status

RUO – Research Use Only