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BAADT

ALX-260-050

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Granzyme B substrate

Chromogenic substrate for granzyme B. λmax is at 405nm.

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Product Details

Alternative Name	Granzyme B substrate (chromogenic), Boc-AAD-SBzl
Appearance	White to off-white crystalline powder.
Formula	C₂₂H₃₁N₃O₇S
MW	481.6
Purity	≥95% (HPLC)
Sequence	Boc-Ala-Ala-Asp-SBzl
Solubility	Soluble in DMSO.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Very hygroscopic.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Improved Purification of Human Granzyme A/B and Granulysin Using a Mammalian Expression System: Rasi, V., Hameed, O. A., et al.; Front. Immunol. 13, 830290 (2022), Reactant(s): Human, Abstract
Human and murine cytotoxic T lymphocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins: S. Odake, et al.; Biochemistry 30, 2217 (1991), Abstract

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