Home Shop Autocamtide-2-related inhibitory peptide

Autocamtide-2-related inhibitory peptide

ALX-151-029

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CaM kinase II inhibitor

Highly specific and potent inhibitor of Ca²⁺/calmodulin-dependent protein kinase II without affecting cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and Ca²⁺/calmodulin-dependent protein kinase IV.

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Product Details

Alternative Name	AIP
Appearance	Lyophilized.
CAS	167114-91-2
Formula	C₆₄H₁₁₆N₂₂O₁₉
MW	1497.8
Purity	≥96%
Sequence	H-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH
Solubility	Soluble in water.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

A novel phospho-modulatory mechanism contributes to the calcium-dependent regulation of T-type Ca2+ channels: J. Chemin, et al.; Sci. Rep. 9, 15642 (2019), Abstract — Full Text
Multiple domains in the C-terminus of NMDA receptor GluN2B subunit contribute to neuronal death following in vitro ischemia: M.M. Vieira, et al.; Neurobiol. Dis. 89, 223 (2016), Application(s): Cell culture, Abstract
Protein kinase C gamma-mediated phosphorylation of GluA1 in the postsynaptic density of spinal dorsal horn neurons accompanies neuropathic pain, and dephosphorylation by calcineurin is associated with prolonged analgesia: G. Miletic, et al.; Pain 156, 2514 (2015), Application(s): Intrathecal injection, Abstract — Full Text
A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II: A. Ishida, et al.; BBRC 212, 806 (1995), Abstract
Stabilization of calmodulin-dependent protein kinase II through the autoinhibitory domain: A. Ishida & H. Fujisawa; J. Biol. Chem. 270, 2163 (1995), Abstract — Full Text

Last modified: May 29, 2024

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Autocamtide-2-related inhibitory peptide

ALX-151-029

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

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