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High affinity selective agonist for the cannbinoid CB1 receptor (Ki= 2.2 nM; CB2 receptor Ki= 0.7 µM). Inhibits forskolin-induced cAMP accumulation, increases binding of GTPγS to cerebellar membranes, inhibits electrically-evoked contractions of mouse vas deferens and production of hypothermia in mice. Active in vivo.
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RUO – Research Use Only |
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