AMPIVIEW® KRT8 (AS) Dig RNA Probes (Human) Set

ISH (in situ hybridization)

AMPIVIEW^® KRT8 (AS) Dig RNA probes (Human) have been designed to target the nucelic acid that encodes for Keratin 8 (KRT8), a type II intermediate filament protein that plays a vital role in the structure and functioin of simple epithelial cells. Overexpression of KRT8 has been linked to tumor progression and metastasis, especially in cancer like clear cells renal carcinoma (ccRCC), breast cancer, colorectal and liver. AMPIVIEW^® KRT8 (AS) Dig RNA probes (Human) are conjugated with digoxigenin and have been optimized to produce clear results with Enzo’s DIGX^® anti-digoxigenin linker and nanopolymner-based detection systems, POLYVIEW^® PLUS, combined with HIGHDEF^® chromogens and counterstain to produce clear results that can be visualized with a light microscope.

2 x 1 mL AMPIVIEW^® KRT8 (AS) Dig RNA Probes (Human) (2µg/mL)
1 x 2 mL AMPIVIEW^® Hybridization Buffer (1X)

AMPIVIEW^® KRT8 (AS) Dig RNA Probes (Human) are optimized for detection of the nucleic acid (RNA/DNA or RNA) encoding KRT8 in FFPE tissues or cells with DIGX^® anti-digoxigenin linker, POLYVIEW^® PLUS detection reagents combined with HIGHDEF^® chromogens and counterstains (linker and detection solutions not included). Dilutions and concentration optimization can be done with AMPIVIEW^® Hybridization Buffer (1X), included in this set.