AMPA

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AMPA receptor ligand

Potent and selective quisqualate analog that interacts with the AMPA subgroup of ionotropic glutamate receptors.

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Appearance	White to off-white crystalline solid.
CAS	77521-29-0
Couple Target	AMPA receptor
Couple Type	Ligand
Formula	C₇H₁₀N₂O₄
Identity	Determined by NMR.
MW	186.2
Purity	≥98% (TLC)
Solubility	Soluble in water (2mg/ml, warm) or DMSO (10mg/ml).

Use/Stability	As indicated on product label or CoA when stored as recommended. Store, as supplied, at 0-4°C for up to 1 year. Store solutions at -20°C for up to 3 months.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Pharmacological agents acting at subtypes of metabotropic glutamate receptors: D.D. Schoepp et al.; Neuropharmacology 38, 1431 (1999), Abstract
The binding of [3H]AMPA, a structural analogue of glutamic acid, to rat brain membranes: T. Honoré et al.; J. Neurochem. 38, 173 (1982), Abstract
New class of glutamate agonist structurally related to ibotenic acid: P. Krogsgaard-Larsen et al.; Krogsgaard-Larsen 284, 64 (1980), Abstract

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