ALDH1L1 polyclonal antibody

The anti-ALDH1L1 antibody enables specific detection of ALDH1L1, a key astrocyte marker and enzyme involved in folate metabolism and detoxification, optimized for IHC applications in neurobiology and metabolic research.

ALDH1L1 is an enzyme in the aldehyde dehydrogenase superfamily that plays a critical role in folate metabolism by catalyzing the oxidation of 10-formyltetrahydrofolate to carbon dioxide and tetrahydrofolate. It is highly expressed in astrocytes, making it a reliable and specific marker for studying astrocytic populations in the central nervous system. ALDH1L1 is also involved in cellular detoxification processes, protecting cells from oxidative damage by metabolizing aldehydes generated during lipid peroxidation and other oxidative stress pathways.