Home Shop AIM2 (human) monoclonal antibody (3B10)

AIM2 (human) monoclonal antibody (3B10)

ALX-804-891

Datasheet
Manual
SDS
CofA

Already have an account?

AIM2 is a strong candidate as a tumor suppressor as it is a member of the HIN-200 (hemopoietic interferon-inducible, nuclear proteins containing a 200 amino acid repeat) family of proteins that have been shown to regulate cell growth and survival. The HIN-200 family of proteins consists of four members in human, IFI 16, MNDA, AIM2 and IFIXl. It has been reported that AIM2 is a receptor for cytosolic dsDNA, which forms an inflammasome complex with ASC to activate caspase-1-mediated processing of IL-1β.

Shipping: Available products typically ship within 24/48h, via priority shipping.

Do you need support? Contact Customer Service or Technical Support.

Online Account
Access or Create Your Account

This antibody is covered by our Worry-Free Guarantee.

Product Details

Alternative Name	Interferon-inducible protein AIM2, Absent in melanoma 2
Application	IF, IP, WB
Application Notes	Detects a band of ~39kDa by Western blot.
Clone	3B10
Formulation	Liquid. In PBS, pH 7.2, containing 0.09% sodium azide.
Gene/Protein Identifier	9447 (Entrez GeneID)
Host	Mouse
Immunogen	Recombinant human AIM2 (aa 1-186) with GST-tag.
Isotype	IgG1
Purity Detail	Affinity purified.
Recommendation Dilutions/Conditions	Western blot (0.5-2 μg/ml)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.
Species Reactivity	Human
UniProt ID	O14862
Worry-free Guarantee	This antibody is covered by our Worry-Free Guarantee.

Handling & Storage

Short Term Storage	+4°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA: T. Fernandes-Alnemri, et al.; Nature 458, 7237 (2009), Abstract
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC: V. Hornung, et al.; Nature 458, 514 (2009), Abstract
Biochemical and growth regulatory activities of the HIN-200 family member and putative tumor suppressor protein, AIM2: K.S. Cresswell, et al.; BBRC 326, 417 (2005), Abstract

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Datasheet

Certificate of Analysis

Please enter the lot number as featured on the product label

Lot No. :

SDS

Enzo Life Science provides GHS Compliant SDS

English (EU) SDS

If your language is not available please fill out the SDS request form

Your Cart

Your Cart

AIM2 (human) monoclonal antibody (3B10)

ALX-804-891

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

Change Country

Tell us about You

Tell us about your paper

Tell us about You

Tell us about your project