AH-6809

BML-RA110

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Prostaglandin E₂ receptor (EP1) antagonist

Selective prostaglandin E₂ receptor (EP₁) antagonist. Useful at concentrations up to 10 µM, at which point it starts to block PGD₂ and TXA₂ receptors.

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Product Details

Appearance	White solid.
CAS	33458-93-4
Couple Target	Prostaglandin receptor, Prostanoid receptor
Couple Type	Inhibitor, Ligand
Formula	C₁₇H₁₄O₅
MW	298.3
MeltingPoint	261-262°C
Purity	≥98% (TLC)
Solubility	Soluble in DMSO.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended. Store, as supplied, at room temperature for up to 1 year. Store solutions at -20°C for up to 6 months.
Long Term Storage	Ambient
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Prophylactic and therapeutic benefits of COX-2 inhibitor on motility dysfunction in bowel obstruction: roles of PGE₂ and EP receptors: Lin, Y. M., Sarna, S. K., et al.; Am. J. Physiol. Gastrointest. Liver Physiol. 302, G267 (2012), Abstract
PTGER1 and PTGER2 receptors mediate regulation of progesterone synthesis and type 1 11beta-hydroxysteroid dehydrogenase activity by prostaglandin E2 in human granulosa lutein cells: Chandras, C., Harris, T. E., et al.; J. Endocrinol. 194, 595 (2007), Abstract

Last modified: May 29, 2024

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AH-6809

BML-RA110

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

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