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Aflatoxin B₁

ALX-630-093

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Mycotoxin

Naturally occuring mycotoxin produced by many species of Aspergillus. Metabolized by the liver to the reactive intermediate aflatoxin M₁. Exposure may produce acute necrosis, cirrhosis and carcinoma of the liver. Induces DNA damage.

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Product Details

Appearance	White to yellow powder.
CAS	1162-65-8
Formula	C₁₇H₁₂O₆
MI	14: 180
MW	312.3
Purity	≥98% (HPLC, TLC)
RTECS	GY1925000
Solubility	Soluble in DMSO (20mg/ml) or methylene chloride (10mg/ml).
Source	Isolated from Aspergillus flavus.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended. May be stored in solution for at least three to four weeks at -20°C.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Bioenergetic Status of the Intestinal and Hepatic Cells after Short Term Exposure to Fumonisin B1 and Aflatoxin B1: Chen, X., Abdallah, M. F., et al.; Int. J. Mol. Sci. 23, (2022), Abstract
Taxonomic Characterization, Evaluation of Toxigenicity, and Saccharification Capability of Aspergillus Section Flavi Isolates from Korean Traditional Wheat-Based Fermentation Starter Nuruk: J. Bal, et al.; Mycobiology 44, 155 (2016), Application(s): Positive control, TLC, Abstract — Full Text
Antimutagenic Effect of the Ellagic Acid and Curcumin Combinations: H. Zoubkova, et al.; J. Environ. Anal. Toxicol. 5, 296 (2015), Application(s): In vivo, bone marrow micronucleus test in mice , Full Text
Mycotoxin occurrence on baled and pit silages collected in Co. Meath: C. McElinney, et al.; Irish J. Agr. Food. Res. 54, 87 (2015), Application(s): Liquid chromatography tandem mass spectrometry for Mycotoxin analysis, Full Text
Aflatoxin B1-induced DNA damage and its repair: L. L. Bedard & T. E. Massey; Cancer Lett. 241, 174 (2006), (Review), Abstract
Hyperplasia, partial hepatectomy, and the carcinogenicity of aflatoxin B1: B.D. Roebu; J. Cell. Biochem. 91, 242 (2004), (Review), Abstract
Activation and detoxication of aflatoxin B1: F.P. Guengerich, et al.; Mutat. Res. 402, 121 (1998), (Review), Abstract
Aflatoxin B1 induced lacI mutation in liver and kidney of transgenic mice C57BL/6N: effect of phorone: H. Autrup, et al.; Mutagenesis 11, 69 (1996), Abstract
A follow-up study of urinary markers of aflatoxin exposure and liver cancer risk in Shanghai, People’s Republic of China: G.S. Qian, et al.; Cancer Epidemiol. Biomarkers Prev. 3, 3 (1994), Abstract
Molecular dosimetry of aflatoxin exposure: contribution to understanding the multifactorial etiopathogenesis of primary hepatocellular carcinoma with particular reference to hepatitis B virus: C.P. Wild, et al.; Environ. Health Perspect. 99, 115 (1993), Abstract

Last modified: May 29, 2024

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Aflatoxin B₁

ALX-630-093

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

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