Acitretin

BML-GR108

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Retinoic acid receptor ligand

Acitretin is a synthetic aromatic analog of all trans retinoic acid with increased stability in vivo. It is the active free acid form of the antipsoriatic drug etretinate. Displays antiproliferative effect and induces apoptosis in Kaposi’s sarcoma cells.

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Product Details

Appearance	Yellow solid.
CAS	55079-83-9
Couple Target	Retinoic acid receptor
Couple Type	Ligand
Formula	C₂₁H₂₆O₃
MW	326.4
Purity	≥98% (TLC)
Solubility	Soluble in DMSO.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

A review of acitretin, a systemic retinoid for the treatment of psoriasis: C.S. Lee & J. Koo; Expert Opin. Pharmacother. 6, 1725 (2005), Abstract
Retinoids: therapeutic applications and mechanisms of action in cutaneous T-cell lymphoma: C. Zhang & M. Duvic; Dermatol. Ther. 16, 322 (2003), Abstract
Antiproliferative effect of retinoid compounds on Kaposi’s sarcoma cells: J. Corbeil, et al.; J. Clin. Invest. 93, 1981 (1994), Abstract — Full Text

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Acitretin

BML-GR108

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

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