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Ac-VDVAD-pNA

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Caspase-2 substrate

Chromogenic substrate for caspase-2. Preferred substrate for caspase-2 (K_m=53μM)

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Alternative Name	Caspase-2 substrate (chromogenic)
Appearance	White to off-white powder.
CAS	189684-53-5
Formula	C₂₉H₄₁N₇O₁₂
Formulation	Lyophilized.
MW	679.7
Peptide Content	70-90%
Purity	≥98% (HPLC)
Sequence	Ac-Val-Asp-Val-Ala-Asp-pNA (pNA=p-Nitroanilin)
Solubility	Soluble in DMSO (100mM). Dilute stock solution with distilled water or buffer.
Technical Info / Product Notes	λmax of pNA is 400nm.

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Keep cool and dry.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Substrate specificities of caspase family proteases: R.V. Talanian, et al.; J. Biol. Chem. 272, 9677 (1997), Abstract — Full Text

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