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Ac-muramyl-Ala-D-Glu-amide

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NALP3 ligand

Specific ligand for NALP3. For inactive control compound see MDP-DD (Prod. No. ALX-151-036).

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Alternative Name	MDP-LD, N-Acetylmuramyl-L-alanyl-D-isoglutamine, Adjuvant peptide
Appearance	White to off-white powder.
CAS	53678-77-6
Formula	C₁₉H₃₂N₄O₁₁
MW	492.5
Purity	≥95% (HPLC)
Solubility	Soluble in water (50mg/ml).
Source	Synthetic.

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	After reconstitution, prepare aliquots and store at -20°C.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Minimal structural requirements for adjuvant activity of bacterial peptidoglycan derivatives: F. Ellouz, et al.; Biochem. Biophys. Res. Commun. 59, 1317 (1974), Abstract

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