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8-Methoxymethyl-IBMX

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PDE inhibitor

Selective inhibitor of Ca²⁺-calmodulin-dependent phosphodiesterase (PDE I, IC₅₀=4 µM).

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Appearance	White solid.
CAS	78033-08-6
Couple Target	PDE
Couple Type	Inhibitor
Formula	C₁₂H₁₈N₄O₃
Identity	Determined by 1H-NMR and MS.
MW	266.3
Purity	≥98% (TLC)
Solubility	Soluble in 100% ethanol (5mg/ml) or DMSO (5mg/ml)

Use/Stability	As indicated on product label or CoA when stored as recommended. Use, as supplied, at room temperature for up to 2 years. Store dilutions at -20°C for up to 3 months.
Long Term Storage	Ambient
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Effects of selective inhibitors on cyclic nucleotide phosphodiesterases of rabbit aorta: H.S. Ahn et al.; Biochem. Pharmacol. 38, 3331 (1989), Abstract
Methylxanthine inhibitors of phosphodiesterases: J.N. Wells & J.R. Miller; Methods Enzymol. 159, 489 (1988), Abstract

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