The alkyne-containing 8-Bu(3-yne)T-Ado is an analogue of adenosine and a suitable molecular tool for the copper-catalysed Huisgen azide-alkyne [3+2] cycloaddition (CuAAC), which has attracted particular interest for the introduction of reporter groups and for the labelling of various biomolecules like binding proteins of adenosine by the so-called click-chemistry technique.
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