8-AHA-cAMP

Site selective cAMP analog with preference for site B of R I of cAMP-dependent protein kinase. In combination with 8-piperidino-cAMP (Prod. No. BLG-P002) which selects site A of R I and site B of R II selective synergistic activation of protein kinase A type I can be obtained. Increased membrane permeability compared to 8-ABA-cAMP [1]. Also suitable as a ligand in affinity chromatography (8-AHA-cAMP-Agarose; Prod. No. BLG-A028) or surface plasmon resonance chip technology [2] and for modification with fluorophores.