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7-Ethoxyresorufin

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Cytochrome P450 substrate

Fluorimetric substrate for cytochrome P450 IA1. Inhibits vasorelaxant responses to acetylcholine.

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Alternative Name	7-ER
Appearance	Red solid.
CAS	5725-91-7
Couple Target	Cytochrome P450
Couple Type	Substrate
Formula	C₁₄H₁₁NO₃
MW	241.2
MeltingPoint	215-220°C dec.
Purity	≥98%
Solubility	Soluble in DMSO (5mg/ml) or 100% ethanol (5mg/ml).

Use/Stability	As indicated on product label or CoA when stored as recommended. Store, as supplied, at room temperature for up to 1 year. Store solutions at -20°C for up to 3 months.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Relaxant responses of rabbit aorta: influence of cytochrome P450 inhibitors: A.O. Oyekan, et al.; J. Pharmacol. Exp. Ther. 268, 262 (1994), Abstract
A microassay for measuring cytochrome P450IA1 and P450IIB1 activities in intact human and rat hepatocytes cultured on 96-well plates: M.T. Donato, et al.; Anal. Biochem. 213, 29 (1993), Abstract

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