- Fast results from up to 38 samples in duplicate in just 3 hours
- Highly specific with low cross-reactivity with structurally related molecules
- Reliable and fully validated in-house with a variety of matrices
- Widely published in peer-reviewed journals
- Save with bulk kit package!
The 6-keto-PGF1α EIA kit is a colorimetric competitive enzyme immunoassay kit with results in < 3 hours. Absorbance is read at 405 nm. This is a highly specific kit with low cross-reactivity to structurally related molecules. The 6-keto-PGF1α EIA kit has been fully validated in-house in a wide variety of sample matrices.
6-keto-PGF1α is a stable hydrolysis product of prostacyclin (PGI2). Due to the short half-life of PGI2 in buffer (2-3 minutes) the production of prostacyclin is typically monitored by measurement of the 6-keto-PGF1α metabolite and its derivative in urine, 2,3-dinor-6-keto-PGF1α. PGI2 has autocoid functions that include platelet aggregation, inhibition of vasoconstrictor responses to pressor hormones, platelet anti- and disaggregatory properties, and reproductive functions. The effects are induced by receptor-mediated elevation of cAMP. Prostacyclin has clinical applications in atherosclerosis and protection from myocardial ischemia.
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Regulatory Status |
RUO – Research Use Only |
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