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6-Bnz-cAMP-AM

BLG-B079

Axxora Marketplace
  • BLG-B079-01   —   1 µmol
    $196.00
  • BLG-B079-05   —   5x1 µmol

The acetoxymethyl group of 6-Bnz-cAMP-AM masks the charged polar phosphate and thus makes the molecule highly membrane-permeant. Inside the cell esterases release the more polar 6-Bnz-cAMP which is a potent, site-selective activator of cAMP-dependent protein kinase. 6-Bnz-cAMP does not activate Epac and thus can be used as an Epac-negative control.
Phosphate tris(acetoxymethyl)ester, PO4-AM3 (Prod. No. BLG-P030), is recommended as control reagent in 6-Bnz-cAMP-AM applications to test for side effects of enzymatically released acetic acid and formaldehyde, two metabolites with potential biological functions.

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Regulatory Status

RUO – Research Use Only