6-Bnz-cAMP

Site selective and membrane permeant activator of cAMP-dependent protein kinase. Increased metabolic stability against PDE compared to cAMP. Selects site A of both cAK isozymes and thus can be used for synergistic activation of PKA type II if combined with site B selective analogues such as Sp-8-CPT-cAMPS (Prod. No. BLG-C012) or 8-piperidino-cAMP (Prod. No. BLG-P002). For preferential stimulation of cAK type I a combination with the site B selective analogue 8-HA-cAMP (Prod. No. BLG-H006) or 8-AHA-cAMP (Prod. No. BLG-A011) can be used.