Home Shop 5-Ketoeicosa-6E,8Z,11Z,14E-tetraenoic acid

5-Ketoeicosa-6E,8Z,11Z,14E-tetraenoic acid

BML-K005

Datasheet
Manual
SDS
CofA

Already have an account?

R527 ligand

Stimulates neutrophil degranulation and Ca²⁺ mobilization by a mechanism independent of the LTB4 receptor. Has been shown to act as an agonist at a G protein-coupled receptor (R527). Induces the infiltration of granulocytes into human skin.

Shipping: Available products typically ship within 24/48h, via priority shipping.

Do you need support? Contact Customer Service or Technical Support.

Online Account
Access or Create Your Account

Product Details

Appearance	Liquid.
CAS	106154-18-1
Couple Target	R527
Couple Type	Ligand
Formula	C₂₀H₃₀O₃
Formulation	Oil dissolved in ethanol
MW	318.5
Purity	≥95% (HPLC)

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended. Store, as supplied, at -80°C for up to 1 year.
Long Term Storage	-80°C
Shipping	Dry Ice

Regulatory Status	RUO – Research Use Only

Expression and characterization of a 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid receptor highly expressed on human eosinophils and neutrophils: C.E. Jones, et al.; Mol. Pharmacol. 63, 471 (2003), Abstract — Full Text
5-oxo-6,8,11,14-eicosatetraenoic acid induces the infiltration of granulocytes into human skin: S. Muro, et al.; J. Allergy Clin. Immunol. 112, 768 (2003), Abstract
5-Oxo-6,8,11,14-eicosatetraenoic acid is a potent stimulator of human eosinophil migration: W.S. Powell, et al.; J. Immunol. 154, 4123 (1995), Abstract
5-Oxo-eicosanoids are potent eosinophil chemotactic factors. Functional characterization and structural requirements: U. Schwenk & J.M. Schroeder; J. Biol. Chem. 270, 15029 (1995), Abstract
Formation of a 5-oxo metabolite of 5,8,11,14,17-eicosapentaenoic acid and its effects on human neutrophils and eosinophils: W.S. Powell, et al.; J. Lipid Res. 36, 2590 (1995), Abstract — Full Text
5-Oxo-eicosatetraenoate, a potent human neutrophil stimulus: J.T. O’Flaherty, et al.; Biochem. Biophys. Res. Commun. 192, 129 (1993), Abstract

Last modified: May 29, 2024

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Datasheet

Certificate of Analysis

Please enter the lot number as featured on the product label

Lot No. :

SDS

Enzo Life Science provides GHS Compliant SDS

English (USA) SDS

If your language is not available please fill out the SDS request form

Your Cart

Your Cart

5-Ketoeicosa-6E,8Z,11Z,14E-tetraenoic acid

BML-K005

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

Change Country

Tell us about You

Tell us about your paper

Tell us about You

Tell us about your project