5-Hydroxymethylcytosine DNA ELISA kit

• Rapid – fully quantitative results in < 3 hours
• Convenient – user-friendly alternative to mass spectrometry
• Simple – efficient and well-established protocol
• High-throughput – 96 well format ideal for global detection, tissue-specific quantitation, high-throughput compound screening, and more

The 5-Hydroxymethylcytosine DNA ELISA kit is a complete, colorimetric, immunometric immunoassay kit for the quantitative determination of 5-hydroxymethylcytosine in DNA  with results in just 3 hours.

The 5-methylcytosine (5-mC) modification of DNA in epigenetic regulation has been well studied over the last several decades. However, the role of the so-called “sixth base”, 5-hydroxymethylcytosine (5-hmC), has yet to be defined. Recent studies have associated 5-hmC patterns to transcriptional regulation of genes, which may contribute to normal and disease states of organisms.