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4-hydroxy-Triazolam

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Metabolite of triazolam

Metabolite of triazolam.

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CAS	65686-11-5
Formula	C₁₇H₁₂Cl₂N₄O
MW	359.2
Purity	≥97% (HPLC)
Solubility	Soluble in DMSO (5mg/ml warm) or methanol (1mg/ml warm).
Source	Synthetic.

Use/Stability	As indicated on product label or CoA when stored as recommended. Store, as supplied, at room temperature for up to 1 year. Store solutions at -20°C for up to 3 months.
Long Term Storage	Ambient
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Triazolam biotransformation by human liver microsomes in vitro: effects of metabolic inhibitors and clinical confirmation of a predicted interaction with ketoconazole: L. L. von Moltke, et al.; J. Pharmacol. Exp. Ther. 276, 370 (1996), Abstract
Metabolism of 8-chloro-6-(o-chlorophenyl)-1-methyl-4H-s-triazolo [4,3-alpha] [1,4]benzodiazepine, triazolam, a new central depressant. II. Identification and determination of metabolites in rats and dogs: H. Kitagawa, et al.; J. Med. Chem. 9, 429 (1979), Abstract
Pharmacology of some metabolites of triazolam, alprazolam, and diazepam prepared by a simple, one-step oxidation of benzodiazepines: M. Gall, et al.; J. Med. Chem. 21, 1290 (1978), Abstract

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